44 Magnum has high damage and is great for early levels. Here’s a list of the 10 best pistols in Fallout 4 to help you on your adventures! Finding the right pistol can be difficult, you may be stuck with a Pipe Pistol or you might have every pistol in the game. They don’t weigh much, ammo is never scarce and they’re a perfect last resort. Every Fallout 4 player needs a trusty pistol at their side.